I disagree a bit with the Republican “line” being drawn at white women (see Hillary Clinton and Wendy Davis). His base is not abandoning him over this insult to White female autonomy, only the other party members with clout outside of his campaign.
No, this has to go deeper for a nuclear apocalypse to happen within his base. He has to be shown smearing some unforgivable crap over the wrong Anglo-American, able-bodied male, the avatar in which most of his base perceive and vaunt themselves. Whatever will destroy him will have to show him, “the Donald”, to be the Emmanuel Goldstein-like “cuck” which they train themselves to most grievously despise.
According to Trump insiders like Hugh Hewett, another shoe is to drop momentarily. It’s supposed to be worse than the “grab them by the pussy” tape.